several very interesting histone modification (epigenetics) papers

Originally published on my old Blogger blog on April 20, 2017. Read the original post and its comments.

If you have read my previous post Misconcept of epigenetics , you will know that: histone modification is not epigenetics!

However, recently, four papers in Science actually showed that histone modifications actually have a component of inheritance:

Causal role for inheritance of H3K27me3 in maintaining the OFF state of a *Drosophila* HOX gene

DNA sequence-dependent epigenetic inheritance of gene silencing and histone H3K9 methylation
Propagation of Polycomb-repressed chromatin requires sequence-specific recruitment to DNA

Transgenerational transmission of environmental information in C. elegans

and one paper in Molecular Cell:

SNF2 Family Protein Fft3 Suppresses Nucleosome Turnover to Promote Epigenetic Inheritance and Proper Replication

one more on Nature Genetics:

Stable Polycomb-dependent transgenerational inheritance of chromatin states in Drosophila

Interestingly, all the studies were carried out on model organisms: Drosophila and C.elegans!

Read this blog post if you are into this question: what is epigenetics ?

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