Transcription-factor

Reviving BETA for Python 3: Integrating ChIP-seq and RNA-seq to Predict TF Targets

I started to learn bioinformatics because I needed to analyze public ChIP-seq data in 2012. That’s how I got to know Shirley Liu’s lab at Dana-Farber Cancer Institute. And God knows that I would join her group in 2020 for a staff scientist position to lead the CIDC bioinformatic project. I witnessed the development of many groundbreaking computational tools for genomics in Shirley’s lab. One tool that I found particularly elegant was BETA (Binding and Expression Target Analysis), developed by Su Wang and published in Nature Protocols in 2013.