https://divingintogeneticsandgenomics.com/tags/mutation/ Recent content in Mutation on Chatomics Hugo -- gohugo.io en-us © 2018 Ming 'Tommy' Tang Tue, 17 Sep 2013 06:19:00 -0700 https://divingintogeneticsandgenomics.com/archive/detect-mutations-from-rna-seq-data/ Tue, 17 Sep 2013 06:19:00 -0700 https://divingintogeneticsandgenomics.com/archive/detect-mutations-from-rna-seq-data/ Usually we detect mutations by DNA-sequencing or whole exome sequencing, GATK http://www.broadinstitute.org/gatk/guide/best-practices is the commonly used pipeline for this purpose. But RNA-seq data can also be used to call mutations in addition to detect the differentially expressed genes. However, the pipelines like GATK is not suitable for this kind of data. A software rnaseqmut was developed by Wei Li in Harvard Dana-Farber cancer Insitute for this purpose See the post here