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    <title>MeDIP-seq on Chatomics</title>
    <link>https://divingintogeneticsandgenomics.com/tags/medip-seq/</link>
    <description>Recent content in MeDIP-seq on Chatomics</description>
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    <copyright>&amp;copy; 2018 Ming &#39;Tommy&#39; Tang</copyright>
    <lastBuildDate>Thu, 23 Jan 2014 12:39:00 -0800</lastBuildDate>
    
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      <title>MeDIP-seq and histone modification ChIP-seq analysis</title>
      <link>https://divingintogeneticsandgenomics.com/archive/medip-seq-and-histone-modification-chip-seq-analysis/</link>
      <pubDate>Thu, 23 Jan 2014 12:39:00 -0800</pubDate>
      
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      <description>I was reading a cell paper:
Dnmt3L Antagonizes DNA Methylation at Bivalent Promoters and Favors DNA Methylation at Gene Bodies in ESCs http://www.sciencedirect.com.lp.hscl.ufl.edu/science/article/pii/S0092867413010878
I want to re-analyze the MeDIP-seq data and the histone modification ChIP-seq data.
I downloaded the MeDIP-seq data here: http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE44644
and the H3k4me3 and H3k27me3 ChIP-seq data here: http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE15519
The paper claimed that Dnmt3L maintains DNA hypomethylation at bivalent promoters ( with both H3k4me3 and H3k27me3 marks).</description>
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