https://divingintogeneticsandgenomics.com/tags/gro-seq/ Recent content in GRO-seq on Chatomics Hugo -- gohugo.io en-us © 2018 Ming 'Tommy' Tang Wed, 30 Oct 2013 18:35:00 -0700 https://divingintogeneticsandgenomics.com/archive/my-first-play-with-gro-seq-data-from-sam-to-bedgraph-for-visualization/ Wed, 30 Oct 2013 18:35:00 -0700 https://divingintogeneticsandgenomics.com/archive/my-first-play-with-gro-seq-data-from-sam-to-bedgraph-for-visualization/ GRO-seq (Global run on sequencing) is a technique to capture nascent RNAs in a global manner. Different from RNA-seq which sequences the matured mRNA to infer gene expression level, GRO-seq sequences the newly generated short RNAs to infer RNApol2 binding or the production of enhancer RNAs. It was first carried out by John T.Lis at Cornell University. See their science paper in 2008: Nascent RNA Sequencing Reveals Widespread Pausing and Divergent Initiation at Human Promoters