https://divingintogeneticsandgenomics.com/tags/genomic-interactions/ Recent content in Genomic Interactions on Chatomics Hugo -- gohugo.io en-us © 2018 Ming 'Tommy' Tang Thu, 03 Mar 2016 20:53:00 -0800 https://divingintogeneticsandgenomics.com/archive/breakpoints-clustering-for-structural-variants/ Thu, 03 Mar 2016 20:53:00 -0800 https://divingintogeneticsandgenomics.com/archive/breakpoints-clustering-for-structural-variants/ Ming Tang March 2, 2016 When structural variants are represented in bedpe format, each structural variant is represented as two linked breakpoints. Each breakpoint is represented as a genomic interval (GRanges). It is very similar to representations of Genomic interactions (data from Hi-C, ChIA-PET): e.g. chr1 100 200 chr2 300 400 one of the common task is to merge the breakpoints when they are overlapping. ———|———|———————–|———-|—– —–|———|————————-|—————|— merged to