<?xml version="1.0" encoding="utf-8" standalone="yes" ?>
<rss version="2.0" xmlns:atom="http://www.w3.org/2005/Atom">
  <channel>
    <title>Epigenetics on Chatomics</title>
    <link>https://divingintogeneticsandgenomics.com/tags/epigenetics/</link>
    <description>Recent content in Epigenetics on Chatomics</description>
    <generator>Hugo -- gohugo.io</generator>
    <language>en-us</language>
    <copyright>&amp;copy; 2018 Ming &#39;Tommy&#39; Tang</copyright>
    <lastBuildDate>Thu, 20 Apr 2017 18:44:00 -0700</lastBuildDate>
    
	<atom:link href="https://divingintogeneticsandgenomics.com/tags/epigenetics/index.xml" rel="self" type="application/rss+xml" />
    
    
    <item>
      <title>several very interesting histone modification (epigenetics) papers</title>
      <link>https://divingintogeneticsandgenomics.com/archive/several-very-interesting-histone-modification-epigenetics-papers/</link>
      <pubDate>Thu, 20 Apr 2017 18:44:00 -0700</pubDate>
      
      <guid>https://divingintogeneticsandgenomics.com/archive/several-very-interesting-histone-modification-epigenetics-papers/</guid>
      <description>If you have read my previous post Misconcept of epigenetics , you will know that: histone modification is not epigenetics!
However, recently, four papers in Science actually showed that histone modifications actually have a component of inheritance:
Causal role for inheritance of H3K27me3 in maintaining the OFF state of a *Drosophila* HOX gene
DNA sequence-dependent epigenetic inheritance of gene silencing and histone H3K9 methylation
Propagation of Polycomb-repressed chromatin requires sequence-specific recruitment to DNA</description>
    </item>
    
    <item>
      <title>Misconcept of Epigenetics</title>
      <link>https://divingintogeneticsandgenomics.com/archive/misconcept-of-epigenetics/</link>
      <pubDate>Mon, 04 Jul 2016 08:39:00 -0700</pubDate>
      
      <guid>https://divingintogeneticsandgenomics.com/archive/misconcept-of-epigenetics/</guid>
      <description>There is a great buzz on twitter discussing what is epigenetics and what is not.
 Epigenetics as a term is meaningless unless it refers to heritability. Otherwise it’s all transcriptional regulation @chrisw_thinkdox @nih
— Einstein Epigenomics (@EpgntxEinstein) April 8, 2016
 I found this PNAS paper is worth to read: Epigenetis: Core misconcept
Some quotes from the paper:
Development is a process involves no changes of underlying DNA. It is driven primary by regulatory proteins called transcription factors (TFs) which binds to specific regulatory DNA sequence to activate or repress gene expression.</description>
    </item>
    
  </channel>
</rss>